OTC
Associated conditions:
- Ornithine transcarbamylase deficiency
OTC makes a liver enzyme that helps the urea cycle turn waste nitrogen into urea for removal. Genetic changes in this X-linked gene are associated with ornithine transcarbamylase deficiency, letting toxic ammonia build up and harm the brain. Knowing your genetic status enables a protective low-protein diet, medicines and rapid treatment of episodes that prevent brain injury.
Conditions linked to OTC
Ornithine transcarbamylase deficiency
OTC deficiency affects the urea cycle that clears ammonia from the body, so ammonia can build up to harmful levels, especially with illness or high protein intake. It is managed with diet, medication and an emergency plan, so knowing your status is important.
