AXIN2
Associated conditions:
- Colorectal cancer
AXIN2 helps switch off Wnt signaling, a pathway that controls how gut lining cells grow and renew. Genetic changes in this gene are associated with an autosomal dominant condition featuring missing adult teeth (oligodontia) and a raised lifetime risk of colon polyps and colorectal cancer. Knowing your genetic status enables earlier, more frequent bowel screening.
Conditions linked to AXIN2
Colorectal cancer
Colorectal cancer develops in the colon or rectum, usually from polyps that turn cancerous over years. An inherited predisposition raises lifetime risk and shifts it earlier, so it is highly preventable with earlier, more frequent colonoscopy that finds and removes polyps before they progress.
