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F5

Associated conditions:

  • Thrombophilia

F5 makes clotting factor V, part of the cascade that forms blood clots. Genetic changes in this gene, most often the factor V Leiden variant, resist the natural shut-off signal from protein C and are associated with an autosomal dominant raised risk of deep vein clots and pulmonary embolism. Knowing your genetic status enables informed care around surgery, pregnancy, and immobility.

Conditions linked to F5

Thrombophilia

Thrombophilia is an inherited tendency to form blood clots more easily than usual. It raises the risk of clots in the legs or lungs, especially around surgery, pregnancy or long travel, so knowing your status guides prevention at higher-risk times.