CDK4
Associated conditions:
- Melanoma
CDK4 makes an enzyme that acts like an accelerator for cell division, telling cells when to grow and copy themselves. Genetic changes in this gene are associated with an autosomal dominant condition called familial melanoma, marked by many unusual moles. Knowing your genetic status enables regular skin checks and sun protection.
Conditions linked to CDK4
Melanoma
Melanoma is a serious skin cancer that begins in pigment-producing cells and can also arise in the eye. Inherited variants raise lifetime risk, so carriers benefit from sun protection, regular skin (and sometimes eye) checks and prompt review of changing moles.
