COL4A3
Associated conditions:
- Alport syndrome
COL4A3 makes one strand of type IV collagen, a mesh that forms the kidney's delicate filtering membrane. Genetic changes in this gene are associated with Alport syndrome, weakening this filter and leading to progressive kidney disease, often with hearing and eye involvement. Knowing your genetic status enables treatment that slows kidney decline and delays failure.
Tests that include COL4A3:
Conditions linked to COL4A3
Alport syndrome
Alport syndrome affects collagen in the tiny filters of the kidney, and also the ears and eyes. It can cause blood in the urine, progressive kidney disease and hearing loss, so early monitoring of kidney function and blood pressure helps protect the kidneys.






