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PKD1

Associated conditions:

  • Polycystic kidney disease

PKD1 makes polycystin-1, a protein on kidney cells that senses fluid flow and keeps tubules properly shaped. Genetic changes in this gene are associated with an autosomal dominant condition called polycystic kidney disease, in which fluid-filled cysts slowly enlarge the kidneys and can reduce their function over time. Knowing your genetic status enables monitoring blood pressure and kidney health that guides timely care.

Conditions linked to PKD1

Polycystic kidney disease

Polycystic kidney disease causes fluid-filled cysts to grow in the kidneys, which can enlarge them, reduce function over time and raise blood pressure. Monitoring kidney function and blood pressure, along with newer treatments, helps protect the kidneys.