MITF
Associated conditions:
- Melanoma
MITF is the master control gene for pigment cells, governing their growth and survival. Genetic changes in this gene, particularly the E318K variant, are associated with a raised lifetime risk of melanoma. Knowing your genetic status enables skin surveillance and sun protection.
Conditions linked to MITF
Melanoma
Melanoma is a serious skin cancer that begins in pigment-producing cells and can also arise in the eye. Inherited variants raise lifetime risk, so carriers benefit from sun protection, regular skin (and sometimes eye) checks and prompt review of changing moles.
